Sentence examples for has potent activity from inspiring English sources

Pro-caspase-3 becomes an active enzyme when two cleaved monomers come together to form an active dimer (Nuñez et al., 1998); this has potent activity, including an ability to autocatalytically activate that contributes to the observed cascade effect of increasing caspase-3 activity as apoptosis progresses.

RATIONALE: Moxifloxacin has potent activity against Mycobacterium tuberculosis in vitro and in a mouse model of antituberculosis (TB) chemotherapy, but data regarding its activity in humans are limited.

A newly released fifth-generation cephalosporin ceftolozane combined with a beta-lactamase inhibitor tazobactam has potent activity against P. aeruginosa, including various MDR types [80].

This indicates that methanolic seed extract has potent activity in the degradation of RNAs of B. subtilis and inhibition of bacterial pathogenic protein synthesis also.

In contrast, voreloxin is not a P-gp substrate [35] and has potent activity in nonclinical models of anthracycline- and etoposide-resistance that include overexpression of P-gp [35].

DRV also has potent activity in vitro against HIV-2.

The result shows that compound 12d and 12h have potent activity reference drug RO-28-1675 RO-28-1675 RO-28-1675

As a result of optimization at the C-3 and 15 positions, several compounds were found to have potent activity against mef- and erm-resistant bacterial strains.

Among them, compounds 5f and 5k were found to have potent activity against erythromycin-resistant Streptococcus pneumoniae whose resistance was encoded by the erm or mef gene.

To our knowledge, this is rarely reported that diarylpyrimidine-based NNRTIs have potent activity against both HIV-1 and HIV-2 in cell culture.

The ability of these compounds to act as antagonists to the androgen receptor was investigated and several were found to have potent activity in vitro.