Sentence examples for has poor permeability from inspiring English sources

However, it has poor permeability and hydrophobicity that obstructs the diffusion of analyte, leading to a fall off sensitivity of the immunosensor.

The mechanism of TFC does not exert central antinociceptive effect could be explained that it has poor permeability across the blood brain barrier (BBB).

Compared with capital, acquiring habitus needs a longer time and has poorer permeability, so it is a more-rigid class barrier that cannot be easily penetrated.

SLN have potential to overcome the solubility and bioavailability problem of the drug that has poor solubility and/or permeability [ 17].

Microcystin-LR has poor cell membrane permeability except for the membranes of hepatocytes (Chong et al. 2000; Eriksson et al. 1990; Nong et al. 2007; Runnegar et al. 1995).

However, CI-1040 was not efficacious against the Drosophila tumour model and has poor aqueous solubility, cell permeability, and is rapidly metabolized compared with PD0325901 Barrettt et al., 2008).

The excavated soil in the shield chamber has poor plastic flow and larger permeability, so it leads to the difficult construction of the EPB tunnel.

Alendronate is a potential candidate for delivery as a polymer conjugate as it has poor oral bioavailability, and poor membrane permeability, both of which could potentially be overcome by this strategy.

Polar compounds with large molecular weight have poor membrane permeability, liposomes can promote drugs to penetrate epidermis and remain or release at dermis.

Compounds of this type are predicted to have poor membrane permeability due to their charge and polarity.

The highest permeability is characteristic for PDMSM, however, it has poor film forming properties.