The evidence from controlled trials and the implementation of stage-and disease activity-adapted regimens have particularly contributed to the improved outcome.
The elements of the course that may particularly have contributed to this positive impact were the group discussions about incident reporting and experiences with incidents that were outlined by teachers and registrars.
More than 50% of breast cancer cases are estrogen-dependent, and treatment with estrogen antagonists that inhibit estrogen receptor (ER) action, particularly tamoxifen, has contributed to a dramatic reduction in breast cancer mortality.
Furthermore, recurrence of the El Nino-Southern Oscillation (ENSO) phenomenon has also contributed to the particularly dry season and intensified the pervasiveness of forest fires.
Booming production in the US, and particularly the shale gas revolution, has also contributed to the recent oil price fall.
Fragmentation of rainforest habitat, particularly extensive in Central America [17], has likely contributed to local extinctions of many Neotropical predators including harpy eagles [10], [18], jaguars (Panthera onca), ocelots (Leopardus pardalis) and margays (L.
The implementation of phase I of the IMCHS Development Cooperation Programme, from 2008 to 2011, has significantly contributed to health sector reform, particularly in the areas of mother and child health.
It is only in relatively recent times that the science of genetics, and particularly population genetics, has contributed to breeding.
And she concedes that the eurozone crisis must take some of the blame: I am well aware that the situation in the eurozone and the European as a whole, but particularly the eurozone, has contributed to this modest growth 1.13pm GMT Coming up... Angela Merkel The next order of business is Angela Merkel's special address to Davos, scheduled to begin shortly.
