Each device, however, has its own particular drawbacks, the most common revolving around cost or inherent difficulties in the production process.In this present report, we will introduce a "movable" OA which does not disturb the physiologic function.
This one-dimensional approach has had two particular drawbacks.
Tamoxifen is the most widely used endocrine agent for adjuvant therapy, but it has drawbacks, in particular an increased risk of thromboembolic events and endometrial changes, including endometrial cancer (EBCTCG, 1998; Baum, 1999).
AO: I don't think there are any particular drawbacks.
This type of capture system has several drawbacks, however; in particular, marker-based systems are expensive, intrusive, and complex to use.
The minimal collection of invariants used by Casanellas and Fernández-Sánchez arises from a statistical framework, but because they were derived using algebraic geometry, this particular list has one drawback.
Olestra, it must be said, does have some drawbacks — in particular, a reputation for what is delicately called "gastrointestinal distress".
3 In particular, imputing by "last observation carried forward" is widely used, 4 but this approach has serious drawbacks.
