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NTDs are the second human disease to be linked to mutations of FZD genes after familial exudative vitreoretinopathy (FEVR; MIM# 133780) that arise from loss of function mutations of FZD4, a FZD gene that has not far been implicated in neural tube closure [ Robitaille et al., 2002].
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Keep driving, you have not far to go.
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He has not so far been accused of any crime.
Yet, he has not thus far.
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