However, no well-designated trials have been conducted to date [9]-[11], and the use of the intravitreal route of administration of TNF-? inhibitors has not been generalized.
However, this valuable service has not been generalized to include all other medications because of limited resources.
The use of the Gram stain has not been generalized because it needs more equipment and time than dipstick analysis, and is unlikely to replace dipstick testing across all health-care settings [ 123].
Although some studies have detected polymorphisms in these genes that alter the risk for preterm birth in either the mother or fetus, the results have generally failed to be replicated [ 39] or have not been generalized across populations [ 43, 44].
While prior work has suggested the transcription of intergenic, antisense, and even circular RNA (circRNA) in P. falciparum, lncRNA transcript models have not been defined and transcript properties have not been generalized on a broad scale [ 41– 41].
Brain-derived neurotrophic factor (BDNF) has been implicated in the pathophysiology of depression and anxiety, but has not been examined systematically in generalized anxiety disorder (GAD).
The importance of each symptom has not been fully established, though generalized skeletal muscle pain, and particularly pain on digital palpation in certain points is considered by the American College of Rheumatology (ACR) to constitute a diagnostic criterion [ 1].
While a number of sensitive staining methods have been developed for protein quantification in solution as well as on solid supports [ 27], these principles have not been extended and generalized for fluorescence microscopy.
Although the Amari model has a hidden energy-type structure, we have not been able to generalize the gradient-structure approach for SPDEs to the stochastic Amari model.
The mechanisms responsible for pancreatic shock have not been elucidated; however, an inflammatory cascade generalized by cytokines and TNF is felt to be the most likely cause of this process [ 17, 18, 19].
After optimization, gain performance was evaluated on the basis of accuracy and efficiency of reaching movements, along with three other benchmark gain sets not optimized for our system, on a large set of dynamic reaching movements for which the controllers had not been optimized, to test ability to generalize.
