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The BRIAN has previously been associated with increased levels of oxidative stress in BD patients (Cudney et al. 2014), but has not been evaluated with other biological measures.
In Europe, however, a comparable prophylactic treatment has not been evaluated with regard to I. ricinus tick bites.
To date, the effect of maternal smoking on differential DNA methylation has not been evaluated with more comprehensive epigenomic coverage than offered by the 27K platform.
To the best of our knowledge, the DASH dietary pattern has not been evaluated with respect to potential influence on diabetes development.
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However, the search-based approaches have not been evaluated with different integration strategies proposed in the literature.
While the rationale for investigating CD4+ T cell responses is based on their potential role in protection against infection in adults [3], [6], memory B cell responses and their relation to circulating antibody titers have not been evaluated with the RTS,S candidate vaccine.
There are several areas of health care which have not been evaluated with methodologically sound studies.
A consistent impairment in attention exists in FES [ 7]; nevertheless, to the best of our knowledge, attention networks in FES patients have not been evaluated with the ANT.
Other widely recommended measures to prevent VAP, such as the semirecumbent patient position and different bundle approaches have not been associated with documented improvements in patient outcome and have not been evaluated with formal cost-effectiveness analyses.
The robustness with respect to sequencing errors in Sanger reads has been investigated and discussed for MetaGene and Orphelia [ 13, 14], other tools have not been evaluated with regard to this property.
Although most recently developed chemical tools for H2S detection have been tested with thiols and afford moderate to good selectivity for H2S over thiols, commonly used chemical tools for thiol detection have not been evaluated with H2S.
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