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Repeated switching between the reference and biosimilar product may present postmarketing safety surveillance challenges to differentiate adverse events for each product; therefore, data should show that repeated switching from reference product to biosimilar (and vice versa) has no negative effect on the safety and/or effectiveness of the products as a result of immunogenicity.
Since being blatantly patronized has no negative effect on me, I went ahead and made the group, tracked down all the email addresses, and sent the information and password to my basketball friends, and I did it in such a way that I'll probably never be asked to set up the bracket again, which was my goal in the first place.
Relative humidity has no negative effect on either pigment [64].
Results revealed that, addition of cerium or gallium has no negative effect on bioactivity and hydroxyapatite forming ability of the glass in long term.
Biogas for rural energy is sustainable, affordable, and has no negative effect on people's health or the environment, if handled properly (Khandelwal & Mahdi 1986; Kumar & Jain 1988).
For direct associations the correlated measurement error usually has no negative effect on the results, while for indirect associations, depending on the relative size of the correlated measurement error, results can become unreliable.
Similar(29)
This reluctance is based on the lack of clear evidence that this procedure has no negative effects.
Lastly, it has been shown that the hydrogen injection has no negative effects on NO emission but induces a strong increase of CO emission.
Electrochemistry shows that the density multiplication has no negative effects on the Pt utilization of the monolayer arrays, and a remarkable ECSA value of ∼114.5 m2 g−1 is found.
Furthermore, Adminsitration of PFC emulsions has been well tolerated by infused animals and has no negative effects on microvascular perfusion [12], [19].
Ang-2 blockage has no negative effects on preexisting atherosclerosis.
More suggestions(14)
has no deleterious effect
has no detrimental effect
has no negative impact
has no bad effect
has no negative influence
has no negative effects
has no negative implications
has no adverse effect
has no adverse impact
has no negative side
has no negative temperature
has no negative energy
has no negative bias
has no immediate effect
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com