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Under the ambitious but not currently enacted Clean Power Plan that would require a 32% cut in CO2 emissions by 2030 from 2005 levels, the use of nuclear energy, which has zero carbon emissions, has no incremental contribution (see Figure below).
Repeated galectin-3 sampling has no incremental value over base-line sampling alone.
Moreover, if we used the simplistic approach of treating the older test as a gold standard, it would be equivalent to assuming that the new test has no incremental (or added) value.
The recent contrast guidelines of the American Society of Echocardiography state that 'the availability of contrast imaging in the [intensive care unit] enhances overall efficiency, diagnostic accuracy, and cost-effective patient management and has no incremental risk for death compared with non-contrast echocardiography' [ 3].
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However, the existing attribute reduction algorithms with VPRS have no incremental mechanisms of handling dynamic datasets with increasing samples, so that they are computationally time-consuming for such datasets.
However, when RNA ejection fraction was first added to the clinical information, myocardial perfusion imaging had no incremental prognostic value.
The court found the pipeline would have "no incremental impact" on the Atchafalaya Basin.
In a recently reported randomized controlled trial of high caries risk adults, a combined antibacterial and fluoride therapy intervention resulted in no difference in the probability of having no incremental lesions in a zero-inflated Poisson model but yielded a statistically significant 24%% decrease in DMFS increment for the count portion of the model [ 11].
These studies demonstrated that the addition of niacin to a statin had no incremental benefit in reducing cardiovascular events (AIM-HIGH) or the risk of heart attacks, strokes, or operations to open blocked arteries (HPS2-THRIVE) in patients with well-controlled LDL-C levels.
That aside, is the prediction that if you were to KO KAP1 and see the effect observed in Figure 1D then the addition of chloroquinone (thought to be active via modulation of KAP1) to KAP1 KO cells should have no incremental impact on HCMV reactivation if the authors predictions are true i.e. if KAP1 mediated repression is deleted by siRNA then any effects of chloroquinone should be abrogated.
The 38-year-old technology investor has no interest in incremental improvements.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com