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Disrupted-In-Schizophrenia-1, preferentially expressed in the forebrain, has multiple isoforms with potential posttranslational modifications.
H1 has multiple isoforms.
Although ELF5 has multiple isoforms, this has not been considered in previous studies of ELF5 function.
When a gene has multiple isoforms, the longest isoform was used.
Conversely, the PP2A/B subunit has multiple isoforms, and it is the major determinant of substrate specificity [ 3].
H1 has multiple isoforms; the subtypes differ in timing of expression, extent of phosphorylation and turnover rate.
Similar(47)
Unlike in C. elegans, higher animals have multiple isoforms of let-7 miRNAs; these isoforms share a consensus sequence called the 'seed sequence' and these isoforms are categorized into let-7 miRNA family.
This implies that regardless of the conservation category of the TFBS, advantageous mutations have predominantly risen to alter transcriptional activity of genes that already have multiple isoforms.
Of the remaining 1073 proteins that were not paired with whole exon array-detected transcripts, 825 (77%) had multiple isoforms detected by mass spectrometry.
Similarly, most alternate Ewing sarcoma translocations have multiple isoforms.
For the proteins that have multiple isoforms the longest isoform was chosen for comparison.
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