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Every drug has multiple actions: it will affect organs and systems beyond those to which it is specifically targeted.
IL-1β is the prototypic inflammatory cytokine and has multiple actions on cells and tissues (reviewed in [ 23]).
Melatonin has multiple actions as a regulator of antioxidant and prooxidant enzymes, radical scavenger and antagonist of mitochondrial radical formation.
CD40 ligand belongs to the TNF superfamily of molecules and has multiple actions that may be of significance within the microcirculation in sepsis [ 140].
Similarly, TNF-α has multiple actions in the pathogenesis of RA [ 31] and may be a contributing factor to OA [ 1].
Similar(55)
But the logic is specious because most drugs have multiple actions.
We conclude that TZDs have multiple actions and that many, but perhaps not all, can be accounted for by their action on adipose tissue.
Such evidence supports the results of earlier research by Kielholz and Poldinger (1968) and Carlsson et al. (1969), indicating that the tricycle drugs have multiple actions, i.e. both tranquilizing and mood-elevating effects.
These findings indicate that PYY and PP have multiple actions but preferentially inhibit neurally mediated pancreatic secretion at a preacinar cell locus, possibly at a central site of action.
Other viral proteins have multiple actions in the host cell, including degrading cellular mRNA and using the released nucleotides for vRNA synthesis and also inhibiting translation of host-cell mRNAs.
Activated AMPK may have multiple actions including the activation of eNOS via phosphorylation at Ser [ 16, 17].
More suggestions(15)
has multifaceted actions
has multiple uses
has multiple benefits
has multiple variations
has multiple shortcomings
has proinflammatory actions
has multiple solutions
has multiple strengths
has multiple functions
has multiple batteries
has multiple isoforms
has multiple inspirations
has multiple hashtags
has multiple effects
has legal actions
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com