In contrast to findings in mice, our data show that HOXA9 has modest effects on the proliferation and differentiation of primary human CD34+ cells.
It is possible that variation at this locus has modest effects on T2DM, but environmental factors may predominate in the progress of T2DM, and mask the effects of this variation.
Here we report that hypusine-modified eIF5A has modest effects on normal protein synthesis, but is required for the rapid polysome disassembly and translational repression observed in cells subjected to arsenite-mediated oxidative stress.
The primer terminal 2′-OH has modest effects on the magnitude of r2.
Miglustat (Zavesca®; Actelion Pharmaceuticals Limited, Allschwil/Basel, Switzerland) is a glucose analogue that can penetrate the central nervous system and which has modest effects on Gaucher disease manifestations.
Audit with feedback has modest effects on professional practice, with effects tending to be greater in settings with little prior exposure to this type of intervention [ 6, 7, 25].
Unexpectedly, the overexpression of Dnm1 alone reduces the length of DsRed-positive neuritic processes by ∼30%, whereas expression of WT LRRK2 has modest effects on neurite length, compared with neurons expressing DsRed alone (Fig. 10B).
The very high titers of this wPP-induced serum antibodies alone had modest effect on reducing B. parapertussis numbers (Figure 10B), consistent with prior results with convalescent serum [30], [39].
First, in general, interventions had modest effect on behavior change [ 10, 11, 14, 16].
Interestingly, MEK/1/2 inhibitors AZD6244 or PD98059 had modest effect on E2-enhanced G6PD expression.
