Sentence examples for has markedly changed from inspiring English sources

The business of tending teeth has markedly changed in a generation or two, dentists say.

During the past ten years, however, the situation has markedly changed.

The landscape for management of IPF has markedly changed with the advent of approved therapeutic options for IPF.

At that time, the arrival of the first biotech drugs has markedly changed the landscape, requiring a completely new approach to pre-clinical development.

A heavy influx of families and non‐manufacturing in dustries — largely from met ropolitan New York and Newark — has markedly changed the character of the Hightstown area since the early 1960's.

The landscape of clinical trial design has markedly changed in recent decades, with a clear emphasis on streamlining drug development towards specific patient populations and indications for investigational agents.

Unlikely as it was, a fight for Saigon would not have markedly changed the equation.

Total joint replacements (TJR) have markedly changed the treatment of debilitating osteoarthritis.

Now, Dr. Smith says, he and others have markedly changed their attitude about sleep problems and aging.

A thematic approach is taken to the courts' interpretation of fundamental rights, showing how judicial attitudes have markedly changed over time.

While it was not clear what prompted the assault, Ms. Nash had markedly changed her hairstyle since the last time Travis had seen her, possibly leading him to mistake her for an intruder.