Increased levels of capital, which must often be committed years before production begins, and before the true market for the product can be established, greatly increase the risks that investors must assume and have markedly affected the investment climate in manufacturing industries.
Participants were excluded if they had any neurological (other than PD), orthopaedic, or cardiothoracic conditions that may have markedly affected their walking or safety during the testing sessions.
We do not expect that typing also the over 30 000 samples negative for HPV by the FDA-approved HC2 test would have markedly affected the HPV type-specific prevalence estimates.
Because the refractive error in their patients was so high, although they did not mention the presence of PPA, most of their subjects were presumed to have a large PPA, 22 which would have markedly affected the retardation pattern of GDx.
However, all were within the post-1991 "folic acid era" and, because folic acid use has been consistently low since folic acid supplementation policies were implemented (Neill et al., 1999; Stockley and Lund, 2008), this argues that variations in the three study periods are unlikely to have markedly affected findings.
The significant downregulation of survivin protein following TBG-siCK2 treatment, but not following TBG-siCDK11 treatment, suggests that downregulation of CK2 in the TBG-siCDK11-treated tumors possibly occurred too late in the acute response study to have markedly affected survivin expression at the time of tumor collection.
However, there was one flock (flock 21) which had markedly different affected genotypes.
The last week before admission, the patient had been markedly affected by headaches and both acoustic and visual hallucinations.
Over the last two decades, the number of individuals infected with human immunodeficiency virus (HIV) has markedly increased, and, actually, > 30 million people are affected with HIV infection worldwide [ 8].
Furthermore, the more application of nitrogen fertilizers has markedly increased the cost in crop production, which greatly affects the income of the farmers.
The same incapacity to form hetero-dimers was observed when TM8 was assayed with either JOINTLESS or the three SEPALLATA-like proteins (i.e. TM5, TM29 and SlMBP21) whose cognate genes had shown a markedly affected expression in the flowers with altered TM8 expression (Table 2).
