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Thus, loss or gain of exons through alternative splicing has major functional implications.
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RNA secondary structures also may have major functional implications for long noncoding RNAs (lncRNAs).
RNA structure also may have major functional implications for lncRNAs as shown, e.g., for the noncoding co-factor MEG3 of the tumor repressor p53[ 27], and the p53 regulated transcriptional repressor lincRNA-p21, which is tethered to hnRNP-K for its proper localization [ 28].
It has major functional and socioeconomic impacts.
This final pledge has major political implications.
The argument has major policy implications.
"This has major commercial implications, it has major security implications," Mr. Erickson said.
It has major staffing implications".
This finding has major clinical implications.
This latter observation has major resource implications.
The existence of CSCs has major therapeutic implications.
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