Another discovery from this analysis is that Q×E interaction occurs independently, regardless whether the locus has main effects.
As a result, both of the QTL can be detected, not only in cases where either of the two QTL has main effects and they have epistatic effects between each other, but also in cases where neither of the two QTL has main effects but they have epistatic effects.
This paper focuses on an approach for selecting informative SNPs, i.e. a small portion of the SNPs that has main effects on the disease, using Random Forests (RF) model [ 9].
These results imply that common variants of intermediate or large effect do not have main effects in the genetic architecture of MDD.
The initial tension, lateral vibration amplitude, cross-section diameter and the modulus of elasticity of the string have main effects on its natural frequencies.
Thus, it can be said that the overstrength factors have main effects on displacement amplification factors for CBFs.
Hierarchical linear modeling of treatment effects over the follow-up period, and analyses of covariance at each assessment point, revealed no interactions between writing and training; however, both interventions had main effects on outcomes, with small effect sizes.
The ANOVA had main effects of Vision (visual condition) and Order (order of learning), and random effect of Subjects.
Here, by specifically examining those single-SNPs which had main effects which did not replicate for pairwise interactions the multiple testing burden is further reduced.
As the allele frequencies deviate from those that are entirely epistatic, one or more SNPs in the model may have main effects detectable by such methods.
