Sentence examples for has made a substantial difference from inspiring English sources

So far, nothing has made a substantial difference in Casey's behavior.

It has made a substantial difference during these last 21 years that Anthony Kennedy got the seat intended for Robert Bork.

I think we had a moment some years ago where it might have made a substantial difference".

Though the higher prices can be a moderate nuisance to real estate businesses or home buyers, they have made a substantial difference to the county budget.

Because of an editing error, a misplaced quote of Wendy Sherman's made it unclear what Hillary Clinton's undersecretary of state for political affairs said might have made a "substantial difference" in Syria.

Program design appears to have made a substantial difference in both static and dynamic benefit incidence.

Nothing seems to have made a substantial difference yet.

These contributions have made a substantial difference in the fight against HIV/AIDS.

Given the methods used, using the median and interquartile range to describe transfer durations, this is not likely to have made a substantial difference to the results.

However, the reported changes are small and unlikely to have made a substantial difference to our measurements, which for IL6 were up to 20 times normal and for TNFα 40 times normal.

Not even the CCI will noticeably affect temperature change within the next 50 years, Reilly says, but "the only way we will get to the year 2100 and look back and say we have made a substantial difference is to start out with firm steps toward a less GHG-intensive world than we otherwise are headed on".