Sentence examples for has made a significant mark from inspiring English sources

The use of the Salmonella assay may not be as lasting as that of the stethoscope, but the Salmonella assay has made a significant mark on the history of toxicology and has an indispensable role to play in the foreseeable future of 21st century toxicology.

Tate Modern's director, Chris Dercon, said the commissions had made a significant mark on the recent history of art.

By then he had made a significant mark on the civil rights movement -- as a teacher, an author, a television commentator and an adviser to activists and politicians.

Back in their ancestral land, several returning Vietnamese and some who shuttle between the two countries have made a significant mark.

Ripken has made a significant difference in major league baseball.

The New York Public Library has made a significant commitment to Internet access.

Within two years, he had made a significant breakthrough.

And we have made a significant start.

Pettitte's presence would have made a significant impact.

"They could have made a significant dent in the situation".

Mr. Obama "hasn't made a significant mark on education" in his years in the Senate in Illinois and Washington, the advertisement asserts.