Sentence examples for has lower affinity from inspiring English sources

The N-terminal actin-binding region of MLCK-210 has lower affinity to actin (Kd = 7.4 μM) than its central D(F/V RXXL repeat-based actin-binding site and does not protect stress fibers from disassembly triggered by MLCK inhibition in transfected cells.

Boggy soil and yellow brown soil showed higher affinities for Cd2+ and Zn2+, respectively, while paddy soil has lower affinity for both cations.

For FcγRIIIa, the key receptor for NK cell-mediated ADCC, there are two polymorphic variants: V158 with higher affinity for IgG1, and F158 that has lower affinity for IgG1.

Interestingly this species effect is seen elsewhere - ICI118551, whilst having high affinity for the human β2-adrenoceptor has lower affinity for the porcine β2-adrenoceptor [32] [34].

In this regard, NFAT5 has lower affinity for DNA than the calcineurin-regulated NFATc proteins, but NFAT5-DNA complexes are more stable than NFATc-DNA ones [6].

Drug 2, which has lower affinity for both receptors, did not significantly alter proliferation of hemangiosarcoma cells, but it is compelling that there was a trend for greater proliferation by the Golden Retriever tumor lines at higher concentrations (1 to 100 nM).

Furthermore, autoreactive T cells are likely to have lower affinity for their target pMHC than virus-specific T cells, consequently making MHC multimer-based detection difficult.

In this study, we attempted to create a lysine-deficient LIGHT mutant that could be PEGylated site-specifically and would have lower affinity for DcR3.

Therefore, they have lower affinity toward amine functionalities, due to the existence of hard soft interaction.

Glycosylation and hydroxyl substituents of anthocyanin had lower affinity to HSA at pH 4, but had relatively potent binding at pH 7.4.

Interestingly, the Δ3KA seems to have lower affinity to phosphatidylinostol bisphosphates than the WT and the Δ2KA.