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As BNP is increased in a variety of cardiac conditions, it offers little help in differential diagnosis and has low specificity for detecting specific cardiac disease such as heart failure [ 2].
Prostate-specific antigen (PSA) screening has low specificity.
Despite its high sensitivity for detecting esophageal cancer, chromoendoscopy with iodine staining has low specificity and requires many biopsy specimens, which is undesirable.
Leukocyte scan is more sensitive but has low specificity.
However, it has become increasingly clear that SP600125 has low specificity for JNK1/2 [18].
Despite excellent sensitivity (95%, range 91 99%), LGE MRI has low specificity (45%, range 37 54%).
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Many studies have shown that the low affinity glucose absorptive route has low specificity- it can transport sugars e.g. L-glucose or rhamnose, or low molecular weight solutes, such as Cr-EDTA, or mannitol, that are not transported by any GLUTs.
Current IASP diagnostic criteria for CRPS have low specificity, potentially leading to overdiagnosis.
Mild cognitive impairment (MCI) case-finding criteria have low specificity in general population studies.
In technical terms, this means the criteria have low specificity: the thoughts or feelings of many normal gamers will be flagged as pathological.
The Seasonal Pattern Assessment Questionnaire (SPAQ), a widely used screening tool, has been shown to have low specificity for SAD.
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