Sentence examples for has low efficacy from inspiring English sources

Pharmacological treatment has low efficacy, often compounded by overuse of medication, and psychological distress in this population is common.

Currently, the Bacilli Calmette-Guérin (BCG) is the only available licensed TB vaccine, which has low efficacy in protection against adult pulmonary TB.

Epinephrine has low efficacy in HAE, but has been advocated for use early in the course of attacks Therapeutic agents available for the treatment of acute attacks of HAE are summarized in Table 3 [232 34]34]; see also the following discussion regarding differential availability of these agents.

However it has low efficacy and provides a low level of absolute DALY gains.

Our results indicating a significantly higher frequency of bone metastases in the first 18 months from the start of trastuzumab treatment merit-specific future analyses to address the possibility that trastuzumab has low efficacy in bone metastases.

While procaine has a high pKa, and consequently has low efficacy in vivo compared to other sodium channel blockers that are commonly used in deactivation studies (Truant and Takman, 1959), recovery from deactivation is faster than with amide local anesthetics such as lidocaine (Sung and Truant, 1954) as ester local anesthetics are metabolized in plasma rather than liver (Covino, 1981).

However, the various vaccines have low efficacy to protect against pandemic strains because of antigenic drift and recombination of influenza virus.

Currently available treatments for patients with medullary thyroid carcinoma (MTC) with residual or recurrent disease after primary surgery have low efficacy rates.

Recent research shows that these herbicides have low efficacy (≤64% mortality) on large wilding P. contorta (height range 1 − 15 m) and P. mugo (height range 0.5 − 5 m) when they are mixed with water and aerially applied at low rates (150 L ha−1) (Gous et al. 2014).

The thalamocortical pathway might thus achieve its effectiveness via high-efficacy thalamocortical synapses or via amplification within cortical layer 4. In rat somatosensory cortex, we measured in vivo the excitatory postsynaptic potential evoked by a single synaptic connection and found that thalamocortical synapses have low efficacy.

Brain tumours have low prognosis with survival rate of only few months and traditional therapy methods such as surgery, radiotherapy and chemotherapy have low efficacy.