Sentence examples for has largely demonstrated from inspiring English sources

And especially since the SPECT/CT is a high-performance device that has largely demonstrated its diagnostic efficiency and that can be used as SPECT alone or as isolated CT.

QoL research in South Africa has largely demonstrated a focus on specific societies (15– 17); socio-economic and healthcare perspectives (15, 16, 18).

While no knockout phenotype has been described for either of these genes in Arabidopsis, studies in rice, maize and Petunia hybrida have largely demonstrated the roles of the AGL6 subfamily in regulating floral organ identity and floral meristem determinacy, indicating redundant roles with closely related genes including SEP[ 9- 11].

Relevant works have largely demonstrated that RapidArc, compared to IMRT, is capable of creating analogous or better dose distributions, compared to IMRT, is capable of creating analogous or better dose distributions, while attaining a reduction in treatment time and monitor units are halved.

Although initial studies have largely demonstrated the role of plant miRNAs in development and morphogenesis processes, there are increasing number of reports indicating that plant miRNAs also target genes involved in biotic as well as abiotic stress responses [ 1, 14, 15].

However, this characteristic has largely been demonstrated at the mRNA level [5], [7], [9], [10].

Among the solid tumors, PD-L1 expression has largely been demonstrated in melanoma, non-small-cell lung cancer, and RCC cells and correlates with poor outcomes when treated with existing systemic therapies [ 34, 35].

In clinical practice, the diagnosis of increased CLCR as a surrogate marker of GFR is important and has largely been demonstrated in burn patients in the setting of antibiotics monitoring: ceftazidime, cefepime, vancomycin and amikacin [ 4, 5, 17, 18].

This includes a commercially available antibody raised against human LAMP2A that has high reactivity to mouse LAMP2A (and8528) and antibodyody raised against the 12 amino acid cytosolic tail of rat LAMP2A which is identical to mouse protein (GLKRHHTGYEQF), and has largely been demonstrated to detect mouse LAMP2A but not other LAMP2 isoforms (Cuervo & Dice, 1996; Cuervo & Dice, 2000b).

Our observations of RA-induced exacerbation of TNBS-induced enterocolitis, as analyzed by survival and neutrophilic inflammation, was surprising because RA has been largely demonstrated to have an anti-inflammatory effect by altering dendritic cell function (Eksteen et al., 2009; Iliev et al., 2009; Westendorf et al., 2009).

The fallacy of this view has been largely demonstrated in previous sections.