Researchers have indicated a substantial potential for cost savings if thiazides are prescribed rather than other more expensive drugs for treatment of hypertension [ 31, 32].
In Tanzania studies have indicated a substantial improvement in the average level of education for women, modernization and communication in the recent years [ 17, 6].
In the last few years, increasing evidence has indicated that a substantial number of microRNA genes are subjected to epigenetic alterations, resulting in aberrant patterns of expression upon the occurrence of cancer.
Previous research has indicated that a substantial number of children and adolescents with mental health problems are not identified by their GP or primary care provider [ 18, 21, 24, 26].
Research has indicated that in a substantial proportion of the youths, anxiety disorders become chronic, causing significant interference with daily functioning for many years [ 4].
Several studies have indicated that a substantial proportion of VLBW infants are disadvantaged in many physical and psychosocial areas during childhood and adolescence [ 2- 4].
In spite of the harmful effects of parental smoking, previous studies have indicated that a substantial proportion of pregnant women still smoke [ 4, 5].
