This population-based observational study revealed that the use of imatinib to treat newly diagnosed CML has increased over the last decade, principally because of increased prescription in patients with fewer comorbidities and less-severe CML.
In Spain, the number of all categories of health professionals per 1,000 population has increased steadily over time, principally nurses, dentists, or pharmacists, whereas the physicians/population ratio has grown more slowly.
Findings indicate that the number of expenditures contributing principally or significantly to gender has increased steadily.
Extended-spectrum cephalosporin resistance has increased during the past few years in nontyphoidal S. enterica, principally in developing countries, where such resistance appears to be endemic in some areas (15 ).
Productivity had increased as a result, they said, principally because of the time saved not having to commute.
Also, in animal studies, AMPK production has been found to increase principally after running.
Exports continued to increase, principally because of the higher price for soy.
Apart from the particle size and shape effect, yttria addition must have principally increased the population of metal-to-ceramic interfaces.
This large increase has occurred principally because of a high intensity of fishing activity by foreign-based vessels and a less dominant, although prominent, role played by locally-based vessels and canoes.
Empirical research in bioethics, principally using the methods of social sciences [ 1, 2]b, has considerably increased during this period (e.g. [ 3]).
