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To determine if the mutated RAbDMvIII has improved specificity towards EGFRvIII, we conducted another western analysis.
R116010 also has improved specificity, suggesting it is less likely to produce adverse side-effects.
The introduction of interferon-γ assays has improved specificity for detecting LTBI compared with the tuberculin skin test [ 15, 16].
Recently, a novel 2-phenylaminopyrimidine derivative named STI571 (formerly CGP57148B) has been reported, which has improved specificity over the tyrphostins (Buchdunger et al, 1996; Druker et al, 1996).
The plaque reduction neutralization assay generally has improved specificity over immunoassays, but may still yield cross-reactive results in secondary flavivirus infections.
The slightly longer five-item version (EPDS5R) that has significantly improved reliability over the EPDS10 may have particular usability for nurse screening given that it is still short, performs well as a stand-alone assessment of depression, and has improved specificity over the three-item version.
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This study has shown that not all of the newer generation ELISAs using recombinant Borrelia antigens have improved specificity compared to older serological assays [ 9, 10].
A double-antibody sandwich ELISA was developed as it was previously shown to have improved specificity for a target cellulase enzyme present in a cellulase enzyme mixture.
These biomarkers may have high enough sensitivity to identify women at highest risk of CIN2 or greater, while having improved specificity compared to HPV DNA testing to further reduce referral of women with MD/LSIL to colposcopy.
The novel three-item version had improved positive predictive value (PPV) over the 10-item version and equivalent specificity to the seven-item depression subscale; the novel five-item provided the best overall performance in terms of ROC and Cronbach's reliability statistics and had improved specificity.
Together, these results suggested that CBU-028 has improved target specificity when compared to 5-NA.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com