We have identified a novel structural class of protein serine/threonine kinase inhibitors comprised of an aminoimidazo[1,2-a]pyridine nucleus.
We have identified a common structural motif that is encoded in all class B GPCR-ligand N-terminal sequences.
We have identified a common structural feature on the surface of four melanoma cell lines isolated from VGP lesions.
We have identified additional unorthodox aquaporins in various insect genomes and have identified a novel common conserved structural feature in these proteins.
Through this exploratory study derived from a basic science perspective we have identified a collection of physical/structural properties of the ECM that change when the ovary becomes malignant.
Structural studies have identified an enzyme−substrate interface, which is expected to overlap with the electrostatic E S interface.
Human space exploration over the last decades has identified major structural and physiological changes in a variety of organ systems due to weightlessness.
As we discuss here, this effort has resulted in a considerable increase in the number of available high resolution structures and inhibitor complexes and has identified novel structural motifs that are available for drug development.
Previous research has identified greater structural musculotendinous stiffness in males than in females, suggesting potential sex differences in joint stability.
16 International research has identified cultural, structural, organisational and personal barriers to women entering medical leadership roles.
