First results confirm that calcite has high affinity for Eu3+.
NPs-Fc has high affinity for the FcRn in the acidic endosome compartments, leading to transcytosis and refraining from lysosomal degradation23.
ScASNase1 is classified as an enzyme belonging to bacterial type II, has high affinity for the substrate and exhibits antineoplastic properties.
Caelyx, due to its pegylation, has high affinity for the skin and a very long circulation time.
In addition, the rehydrated LDH, with a net positive surface charge, has high affinity for negatively charged PHF through an electrostatic interaction.
FE 200 440 has high affinity for the human cloned oxytocin receptor, approximately 300-fold that for the vasopressin V1a receptor, whereas atosiban binds well to both receptors.
Subsequent optimisation resulted in identification of 19, which has high affinity for the dopamine D3 receptor (pKi 8.3) and ≥100-fold selectivity over other aminergic receptors.
Interestingly, whereas 1 and 2 and their analogues have only moderate affinity for the human D4 receptor, 5 also has high affinity for this isoform.
SOM230 has high affinity for sst1-3 and sst5[27], while KE108 has high affinity for all five sst1-5[28 sst1-5[28
It is absorbed into bloodstream as it has high affinity for proteins, which leads to inhibition of the red blood cells.
The opioid antagonist agent naloxone hydrochloride (NLX) is a drug that has high affinity for opiate receptors but do not activate these receptors.
