Sentence examples for has extensive interactions from inspiring English sources

Here we report the crystal structures of the yeast BC domain, alone and in complex with soraphen A. Soraphen has extensive interactions with an allosteric site, about 25 Å from the active site.

In our model of the TLR4 homodimer the interface has extensive interactions involving the BB loops of the two subunits.

In addition, although the structure of the N-terminal region of legumain (about 25 residues) is not available, an ordered C-terminal domain is present in the structure of the zymogen [ 9], which has extensive interactions with the peptidase domain (PDBePisa [ 88]) and also blocks the S1-binding pocket.

(C ) The same region in (B ) but with the CP dimer (purple), showing that the N-terminal loop of MCP hydrogen-bonds to β-strand C of CP (black circles) to form an augmented 10-stranded β sheet, and that the C-terminal loop (red circles) of each CP has extensive interactions with nearby MCP molecules.

Unlike granisetron, serotonin has extensive interactions with residues in loop E (Fig 3A,C), including hydrogen bonds with the backbone atoms of I104 and I116 (homologous to Y141 and Y153 in 5-HT3R) and hydrophobic interactions with V106, M114 and F115 (homologous to Y143, Q151 and N152 in 5-HT3R).

TGFβ can lead to proliferation arrest and has extensive interaction with p53 (Adorno et al., 2009; Massague, 2008).

"These were clients we had extensive interactions with over several months, sometimes with as many as 50 meetings.

Federal prosecutors have their strongest case against Stein, who had extensive interactions with the undercover officer he thought was a high-level weapons dealer.

John Mehno, a reporter who had "extensive interactions" with Ellis over his career, was skeptical about many stories told by Ellis, including the LSD no-hitter.

Monomers stacked on top of each other (A and F; Fig. 3b) have extensive interactions that are significantly enhanced by a 'swapping' of N-terminal residues.

Splicing has been shown to have extensive interactions with transcription processes and other pre-mRNA processing events [ 13].