Sentence examples for has extensive effects from inspiring English sources

The various arms of the vertebrate immune response are interdependent, and the upregulation of one arm has extensive effects on the expression of other immune modes; the TH1/TH2 inhibitory dicotomy is a well known example of this effect.

Our results demonstrate that the extra or missing chromosome has extensive effects on the whole transcriptome.

Based on the high quality next generation whole transcript sequencing results in this study, we propose that an extra or missing chromosome has extensive effects on the whole transcriptome.

AM2 is a more recently discovered member of the AM family (Roh et al., 2004; Takei et al., 2004a, b) and, along with AM, has extensive effects on the CVS including vasodilatation, cardioprotection, modulation of vascular tone and stimulation of angiogenesis (Hinson et al., 2000; Fujisawa et al., 2004; Takei et al., 2004a, b).

It has been demonstrated that PNS have extensive effects on the cardiovascular system, including inhibition of platelet aggregation, increasing blood flow, improving left ventricular diastolic function in hypertensive patients and anti-inflammatory effect.

To date, much of the focus on digital currencies has been directed at their potential to substitute for or complement fiat currencies, but the true innovation lies in their underlying infrastructure – the decentralised ledger of transactions called the 'blockchain', which could have extensive effects in myriad applications.

The 1998 bleaching event had, and is still having, extensive effects across the western Indian Ocean.

Microarray studies suggest that epigenetic factors can have extensive effects on levels of gene expression [7].

Global changes in chromatin remodeling, in turn, are shown to have extensive effects on gene expression in multiple contexts [21] [23].

Our results show that the microbiota have extensive effects on hepatic gene expression in mice, demonstrated by higher expression of a number of key genes in metabolic function, most notably CAR, in GF mice as compared to conventionally-raised specific pathogen-free (SPF) animals.

Nucleoli likely provide a keystone for genome architecture [ 64– 67], suggesting that disruption in the organization of rDNA could have extensive effects on the organization and expression of most chromosomes such as that observed at NADs.