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Our results demonstrate that the PXY-CLE pathway has evolved to regulate secondary growth and manipulating this pathway can result in dramatically increased tree growth and productivity.
Each gene has evolved to regulate a specific area of myogenesis.
This makes it a prime target for a bacterial protein that has evolved to regulate intracellular trafficking.
In addition to providing structural support to tissues, the ECM has evolved to regulate intercellular signaling pathways, for example by binding to growth factors and regulating their distribution or activity in the extracellular space (Hynes, 2009).
Achieving a level of understanding for how genomic codon usage bias has evolved to regulate gene expression in organisms will greatly facilitate the development of synthetic DNA design parameters for optimal heterologous protein production.
Besides its role in suppressing repeat elements in the genome, DNA methylation has evolved to regulate certain biological phenomena that need to change within an individual's lifetime (e.g., development and differentiation, response to environment), yet still retain a certain level of stability [ 45, 46].
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Critically, humans have evolved to regulate Fc glycan modifications for immune homeostasis.
Circadian clocks have evolved to regulate physiologic and behavioral rhythms in anticipation of changes in the environment.
The serpins comprise an ancient superfamily of proteins, found abundantly in eukaryotes and even in some bacteria and archea, that have evolved to regulate proteases of both serine and cysteine mechanistic classes.
MIRO GTPases have evolved to regulate mitochondrial trafficking and morphology in eukaryotic organisms.
It provides further insight into how novel ways have evolved to regulate the formation of the cuticle, which is the primary protective barrier and skeletal component of nematodes.
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