Sentence examples for has established role from inspiring English sources

Remarkably, HOXD3 gene, adjacent to HOXD-AS1 locus, has established role in promoting metastatic potential of lung cancer cells [ 45].

Cholesterol also has established roles in gallbladder disease [ 21, 32] and modifies other gastrointestinal functions.

Dlk1 has established roles in influencing proliferation and differentiation of several tissues, including adipose [ 50, 72– 74] and skeletal muscle [ 55].

HIF has established roles in the response to hypoxia (Moniz et al., 2014; Semenza, 2011), and several studies using cell-specific HIF-α knockout have established a role for HIFs in the immune response.

Although CGRP has established roles in central nociceptive transmission and neurogenic inflammation in peripheral tissues (17, 18), its role in modulating peripheral nociception is poorly understood.

Although some peripheral clocks have established roles [1], it is unclear what local brain clocks do [2, 3].

We use live-cell imaging to visualize, localize and quantify proteolysis as it occurs in real-time and thereby have established roles for lysosomal cysteine proteases both pericellularly and intracellularly in tumor proteolysis.

Roberto: For the most part, we have established roles when it comes to making music.

CXCR4 receptors have established roles in tumor metastasis [11].

However, only a fraction of these proteins currently have established roles in splicing.

Genes from exC3 which have established roles in AD and psoriasis include SPINK5 [5], FLG [6] and CDSN [7], [8].