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However, Au has drawbacks when combined with the most popular semiconductor, silicon (Si), because Au atoms incorporated into Si induce deep level electrical defects [16, 17].
However, as we discussed above, this typical computational scheme for global metric has drawbacks when applied to PPI network analysis such as the determination of optimal dimensionality and the computational difficulty due to the large size and singular matrix.
However, each of these methods has drawbacks when considered for wide use in the amplification of target regions.
Reverse phase liquid chromatography (RPLC) is the method of choice for separations but has drawbacks when applied to intact proteins, such as irreversible protein adsorption to the stationary phase.
Case cross-over analysis has drawbacks when applied to more than one pollutant at a time (e.g., diminished statistical power as pollutants are added, difficulties identifying higher order interaction, confounding from correlation) [ 14, 16- 18].
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Popular meta-heuristic algorithms including genetic algorithm and particle swarm optimization (PSO) have shown to have drawbacks when the solution to be found is multimodal.
But it's important to note that Clinton does have drawbacks when it comes to religious intrusion in government.
Thus, if one is interested in the most efficient methods to compress the raw reads, reference-based methods can have drawbacks when compared with de novo approaches.
Although it is an effective approach to design stable closed loop systems for nonlinear controlled systems, it has drawbacks to become extremely complex when the relative order of the controlled system is large.
Filling the tank with regular-grade gas when premium fuel is recommended has drawbacks.
But it has drawbacks.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com