Sentence examples for has differentiated to from inspiring English sources

Thus, our results suggest that the residual Oct4 population of cells is not a population of ESCs resistant to differentiation but instead is the population of cells that has differentiated to the germ cell lineage rather than the somatic lineages.

Our results indicated that hiPSCs had differentiated to neural cells completely after incubation time.

Hematoxylin-eosin-stained sections from harvested tumors revealed cells that had differentiated to osteogenic (Fig. 2C, E), cartilaginous (Fig. 2F, G), or neural lineages (Fig. 2H, I) among the undifferentiated cells (Fig. 2C, D).

This is also consistent with conclusions from lineage tracing studies using the BAC Ascl1::CreER transgenic mouse which showed 30 days post-TAM all Ascl1 lineage marked cells had differentiated to neurons in the olfactory bulb [7].

However, once cells have differentiated to form committed endothelial precursors, PRH expression is lost in these cells [ 9].

At 66 h, the cells have differentiated to form large polarised multinucleate cells that resemble syncytiotrophoblast in vivo.

Remarkably, after duplication, the genes were conserved during evolution and probably have differentiated to assume various functions related with tissue mineralization specificity.

These cells are negative for Six2 and Ncam1, suggesting that they are at a stage preceding the progenitor stage or have differentiated to a completely different fate.

This suggests that the anti-LSA antibody response may have differentiated to long lived plasma cells which have a 140 day half-life [ 39] and are largely unaffected by immunosuppressive chemotherapy [ 40, 41].

This is consistent with moderately enhanced positive selection of HY cells to the CD8+ T-cell lineage in female C2HY mice, as more of the Tet+ cells have differentiated to SP8.

We posited that rational design could be similarly effective in elucidating how homologous aaRS architectures have differentiated to select among the large number of amino acids present in the cell.