However, the development of new therapeutic strategies with a better control of extra-cranial disease and a longer overall survival (OS) has determined an increased incidence of brain metastases.
The City Council has determined that increased environmental degradation and hazards for pedestrians, intolerable vehicle congestion, and a general deterioration of quality of life for the residents are more than offset by the increased revenues that IKEA will generate for the city.
The increasing life expectancy of the population in the Western countries has determined an increase of chronic diseases, with cardiovascular disease being one of the most prevalent pathologies[ 1].
Although the possibility of signalling between LOX and vinculin has not been determined, increased vinculin expression reportedly enhanced focal adhesion formation and reduced cell migration, as shown with LOX knockdown in mTECs (Coll et al, 1995; Humphries et al, 2007).
We therefore measured FlhDC dependent phenotypes in order to better understand what has determined the increase in virulence during our selection experiment.
The high incidence of multidrug-resistant (MDR) bacteria among patients admitted to ICUs has determined an increase of tigecycline (TGC) use for the treatment of severe infections.
Although the pathological roles of cell injury and apoptosis in the epithelium of the airways during acute lung injury and fibrosis have not been fully determined, increased apoptosis of alveolar epithelial cells (AECs) has been observed in IIP, not only in the fibrotic lesions, but also in histologically normal alveoli [ 12- 15].
Scoppa (2010a) shows that the 1990 reform introducing a more stringent employment protection legislation for small firms in Italy has determined a significant increase in employee absenteeism in these firms compared to large firm employees unaffected by the reform.
The Gail model, however, has determined an apparent increase in risk with early first pregnancy and it would appear to be misplaced from our results, and from subsequent studies published on BRCA1/2 [ 22, 23].
Guided in part by Harvard economist Edward Glaeser's book Triumph of the City, the Downtown Project has determined that it needs to increase the neighborhood density to 100 residents per acre (high density is an ideal put forth by Glaeser), from what it says is 14.5 currently.
