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One of these molecular approaches could be the design of peptides containing the functional domain of certain cytokines, exemplified by IT9302, a peptide homologous to the functional domain of IL-10, which has demonstrated to increase tumor NK cell sensitivity.
Furthermore, targeting of catalase to mitochondria in transgenic mice has demonstrated to increase murine life span (Schriner et al. 2005).
Also, oxaliplatin combined with LV-FU has demonstrated to increase significantly the response rate and the time to progression, but not the survival, in comparison with the same regimen without oxaliplatin (de Gramont et al, 2000).
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The photocatalytic modules CdS shell)/metal (core)/TiO2 heterostructures, have demonstrated to increase visible light harvesting significantly and to increase the photocatalytic hydrogen evolution activity.
Exposure to air pollution has been demonstrated to increase the risk of preterm birth and low birth weight (LBW).
IL-6 has been demonstrated to increase RANKL expression from osteoblasts and thus stimulate osteoclastogenesis.
Don't use turmeric if you suffer from gallstones or a bile duct obstruction, as turmeric has been demonstrated to increase the flow of bile.
Dietary nitrate (NO3−) intake has been demonstrated to increase NO bioavailability in humans.
Prolonged labor has been demonstrated to increase adverse maternal and neonatal outcome.
In both experimental and clinical (pancreatitis) studies, hyperchloremic acidosis has been demonstrated to increase the release of inflammatory mediators [93],[94].
For instance, cryomilling of NiCrAlY powder, which has been demonstrated to increase TBC lifetime, results in unintentional Fe additions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com