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Global microRNAome profiling has demonstrated significant changes in the expression of multiple miRNAs in a growing list of human diseases, including neurodegenerative diseases [20], heart diseases [21] and cancer [22].
Previous work has demonstrated significant changes in NOS expression, and moreover a functional role for NO, in animal models of chronic neuropathic pain.
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"By the end of 2010 we need to have demonstrated significant changes," he said.
Previous studies have demonstrated significant changes in red blood cell (RBC) transfusion practice over several decades.
During the last decade various research groups have demonstrated significant changes of bioelectrical activity in the visual cortex of migraine patients over the migraine cycle.
For example, some studies reported that instructional treatments did not meaningfully affect teacher evolution acceptance levels, even in cases in which large learning gains were found (e.g., Nehm and Schonfeld 2007), whereas others have demonstrated significant changes in acceptance but not knowledge (e.g., Nadelson and Sinatra 2010).
Several studies have demonstrated significant changes of miRNA expression levels in CCA tissue in comparison with paired noncancerous bile duct.
Other studies have demonstrated significant changes in systemic cytokine levels for subjects treated with ACE inhibitors [ 6- 8].
Studies from our laboratory [ 3– 5] and others [ 20] have demonstrated significant changes in the RAS in response to antenatal MLPD.
Previous studies have demonstrated significant changes in anxiety-related and depression-related symptoms between 1 week and 3 months following an mTBI.
22 Previous studies have demonstrated significant changes in anxiety-related and depression-related symptoms between 1 week and 3 months following an mTBI.
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