Although some studies have shown good inter-observer agreement, especially when evaluating metastasis [4 6], others (mostly primary tumor studies) have demonstrated rather poor agreement with a resulting high risk of misclassification [7 9].
This is in contrast to recent reports, which have been performed in embryonic stem cells that have demonstrated rather an additive effect of both genes on 5-hmC formations.
Furthermore, studies with gene-targeted mice have demonstrated rather convincingly that individual MMPs perform functions that do not overlap with the role of other MMPs (Gill et al., 2010b).
As decision aid interventions in the treatment of cancer patients have demonstrated rather small effects across diseases, future research may address the role of contextual factors that promote the implementation and effectiveness of shared treatment decision making.
Further TEM analysis of the carbon nanotubes grown on top of alumina membrane with S1813 photoresist has demonstrated a rather good quality of the grown nanostructures with relatively thin walls consisting of approximately 10 atomic carbon layers (Figure 6a,b).
Applicants should focus proposals on the science questions in which the applicant has demonstrated expertise rather than extending beyond core strengths simply to address many topics.
The comparative analysis above has demonstrated how a rather similar trend in activation policies for newly arrived immigrants in Sweden, Norway, and Denmark took place from the early 1990s until 2015.
15 Further, more recent evidence has demonstrated an increase, rather than a decrement, in metabolic markers of bile acid synthesis.
Notwithstanding, a randomised prospective clinical trial has demonstrated that immediate rather than delayed androgen deprivation in patients with lymph node-positive metastases following radical prostatectomy results in an increased median survival of 2.6 years with a mean follow-up of 11.9 years (Messing et al, 2006).
