Sentence examples for has demonstrated no effect from inspiring English sources

A report of the VICTOR study, which was a phase III placebo-controlled trial of rofecoxib in non-metastatic colorectal cancer patients, has demonstrated no effect on overall survival (OS) when compared with placebo, but there is a suggestion of a protective effect against recurrence, though this was not statistically significant (Midgley et al, 2010).

An arbitrator overturned Commissioner Bowie Kuhn's suspension of pitcher Ferguson Jenkins after a drug arrest in 1980 in part because Jenkins had been placed on administrative leave and the arbitrator found that management had demonstrated no effect on baseball's business.

While research has provided some general support for the effectiveness of such substances in reducing exercise-related muscle soreness [10, 16], previous studies specific to ultramarathon running have demonstrated no effect.

Indeed, some studies have demonstrated no effect [ 14] while others have suggested that these conditions increase the expression of these proteins [ 15- 17].

In nonhuman primates, high cumulative exposures to Mn > 300 mg/kg show reduced striatal concentrations of dopamine (Bird et al. 1984; Eriksson et al. 1987b; Neff et al. 1969); however, studies using lower doses have demonstrated no effect of Mn on dopamine levels (Olanow et al. 1996; Struve et al. 2007).

The recently completed dal-VESSEL study has demonstrated no adverse effects of dalcetrapib on arterial blood pressure or endothelial function.

It has also been shown to produced neurotoxic reactions in cell bodies located within the B9 region of the raphe nucleus, while 4-fluoroamphetamine has demonstrated no detectable neurotoxic effect [ 16, 17].

Nevertheless, although one reported study has demonstrated no relationship between the effect of online formative assessments and overall student performance in a program as measured by grade point average [ 16], the design of our study cannot exclude such a relationship.

Several studies have demonstrated no adverse effect on local recurrence and overall survival in patients undergoing limb salvage surgery compared with those undergoing amputation.

In accordance with our findings, another oocyte study had demonstrated no significant effect of altering cRNA transfection ratio on the sensitivity of WT α4β3δ receptors to GABA or Zn2+ (Borghese and Harris, 2007).

Conversely, drugs that have demonstrated no adverse effects in selected animal species may in fact be human teratogens [ 5].