Sentence examples for has demonstrated in model from inspiring English sources

Waters has demonstrated in model β-hairpin peptides that phosphorylation disrupts β-hairpin formation, whereas OGlcNAcylation at a different residue stabilizes the β-hairpin, both via native effects of the post-translational modifications on the β conformation and via either repulsive (phosphorylation) or attractive (OGlcNAc) interactions with a cross-strand tryptophan residue.

Previous studies have demonstrated in model organisms and human cells that CHD1 remodelers are recruited to promoters in a gene expression-dependent manner [ 29, 30].

"He's got a good concept and has demonstrated in computer models that you can arrest a tornado," Bryant says.

However, it is important to keep in mind that the level of α-ketoglutarate would be much more tightly regulated than what we have demonstrated in the model.

Several authors have demonstrated, in various models of cancer (including the breast), the ability of Vitamin D to perform autocrine and paracrine functions.

Hence, removal of senescent cells is beneficial and has been demonstrated in model animals [ 84].

In addition, a highly selective, reversible BTK inhibitor, CGI-1746, has demonstrated efficacy in mouse models of inflammation.

Preclinical use of anti-NGF antibodies has demonstrated efficacy in rodent models of inflammatory and neuropathic pain [ 16].

CD40 ligand (CD40L) blockade has demonstrated efficacy in experimental autoimmune models.

Vaccine therapy has demonstrated promise in preclinical cancer models, although this promise has yet to translate into consistent clinical efficacy.

Here, glyco- or protein engineering of antibodies' Fc region has demonstrated promising activity in preclinical models.