As Timothy James, an economist at Arizona State University said, "Arizona trades on people". Without CAP, he said, "it definitely would have been difficult for developers to build more housing and would have constrained the number of people who moved here". In reality, as described in his 2014 paper, CAP's impact was transformative.
To be more consistent across our different analyses, we have now specified a criterion for this limitation: we have constrained the number of clusters so that no more than 5% of all the genes in the analysis belong to "non-representative" small clusters, defined as containing less than 1% of all the genes in the analysis.
The side effects of the computer are only the latest in a relentless number of ways that modern civilization has constrained the human body.
In particular, the small number of African American male subjects may have constrained the outcomes further.
Finally, the numbers of events in both primary and secondary outcomes were small and, as such, may have constrained the identification of statistical significance.
While in theory TreeMap can find optimal solutions, Page et al. had to constrain the number of host switches to 3 in order to solve the problem in a reasonable amount of time and memory.
By then, the virus had busted past the first set of public-health responses that could have constrained its spread, and the number of Americans diagnosed with AIDS leapt from dozens in 1981 to two hundred and six thousand a decade later.
Germany had limited access to oil, and thus to aviation fuel, and this constrained the number of missions the Luftwaffe could fly.
