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But all that has changed, largely because of Pratt and the Navy Yard.
That races in Washington State, California and Oregon — all traditionally friendly to Democrats — still need visits from the campaigner in chief to energize the base is a sign of how much the political landscape has changed, largely as a consequence of the economic downturn.
In recent years this picture has changed, largely due to the introduction of new experimental methods to reveal cell types and their connectivity.
In recent years, the therapy of AS has changed, largely due to the introduction of inhibitors of the proinflammatory cytokine tumor necrosis factor (TNF).
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Times have changed, largely because incomes have risen -- in a few cases well into six figures.
Decades ago bands and promoters used to split this money more evenly, but as the economics of the industry have changed — largely through national consolidation and more competitive bidding — the balance has shifted to the benefit of the bands, with major acts routinely getting 90 percent, or even more.
The role and identity of NGOs have changed largely during this legal review, as shown by the facts that environmental institutions took civil society into consideration and that the Supreme Court sought the support from the society in the formulation of judicial interpretation.
All of our characters have changed, largely for the better.
As Issenberg shows, that has changed, thanks largely to the efforts of the political scientists Alan Gerber and Donald Green.
What has changed is largely a matter of degree, and partly perhaps of sophistication.
The definition of disability under the law actually has changed since 1980, largely to encompass more conditions that are truly disabling.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com