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But if after RF shift the protein has changed its function, then it is of great interest to understand how changes in amino acid sequence determine the protein's new function.
"The building has changed its function," says de Vaux.
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This protein is most similar to PARP1 homologues indicating that the mutation which may have changed its ADP-ribosylation function (poly vs mono(ADP-ribosyl)ation) occurred after horizontal gene transfer.
One of these receptors (Dappu_InR-4) has likely changed its function but does not appear to be under positive selection.
"If Facebook wanted to enter China, it would not have to change its function, because netizens here are used to copycats already, but it must, like other international internet companies, obey Chinese laws and regulations," said Hu Yong, a professor at Beijing University's school of journalism and communication.
"Amazon.com has changed the function of a bookstore," Mr. Herold explained.
The world has now elected sportswear as its ruler, but the Acne show for the 21st century showed how much has changed: Function now leads form, with the blouson jacket or denim bomber that opened the show looking almost vintage, compared to airy nylon parkas and stretch incorporated into shorts and tops.
Since then its main function has changed to local governmental administration, and it has important livestock sales and a campus of Borders College.
In vertebrates, mir-9a has a quite different role in positively regulating neurogenesis, indicating that both its expression and function has changed significantly in the vertebrate group or this developmental role of mir-9a is particular to the insect group.
Sasi encompasses fishery-related rights and rules, and is therefore commonly referred to as a traditional resource management institution, even though it also has other functions and its focus has changed through time [32].
As is shown in Table 5, all the interaction terms between marriage cohort and the duration of marriage (including its square term) are statistically significant, which indicates that the shape of divorce risk function has changed significantly over time.
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