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Loss of other life forms has big impacts.
As nuclear hormone receptors play important roles in circadian clock input and output pathways, it is not a surprise that SIRT1 also modulates the activities of different nuclear receptors and has big impacts on the functions of nuclear receptors in cellular metabolism, which is closely linked to circadian clocks.
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Microsoft has big impact; Intel does, and presumably the next Intel would.
The ability to scale the operating voltage with frequency of the chip has big impact on power consumption (Pαv2).
Big structures have big impacts on the environments around them.
Fortunately, relatively small investments can have big impacts.
Challenge and push yourself, but realize that small changes and tweaks can also have big impacts.
Therefore, heatwaves can have big impacts on public health.
With a disease like DMD, however, even small reductions in symptoms can have big impacts on quality of life.
Shaping 2003 Low Interest Rates Had Big Impact But 2003 was not an ordinary year.
In security, you can have big impact," he says.
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CEO of Professional Science Editing for Scientists @ prosciediting.com