While the induction of antioxidant properties has been well-attributed to Nrf2, we and others have demonstrated the role of Nrf2 in the regulation of inflammation.
Its antioxidant capacity has been well studied and attributed to its polyphenolic content, namely, flavonoids and phenolics [ 49].
In the case of T-ALL and MDS, an oncogenic role of JMJD3 has been well documented, which was largely attributed to its specific partnership with NF-κB and NOTCH15,21, two TFs whose overactivations are highly associated with the induction of multiple types of inflammatory cytokines and the proliferation of T cells3,40.
The existence of a transmural APD gradient has been well established and has been attributed to differences in IK density [21] [23].
If the anaesthesia report has been well done it is possible to attribute a Larach Clinical Grading Scale that classifying the reactions as" almost certain" (more than 50 scores) or very rare "almost never" with 0 scores.
Lack of condom use with regular partners has been well documented among sex workers and is attributed to a desire both for greater intimacy with regular partners and as a means to differentiate work life from personal relationships [ 11, 18, 19].
The role of remote sensing in measuring and monitoring forest area, and assessing its structural and functional attributes, has been well documented [2-4].
The role of remote sensing in measuring and monitoring forest area, and assessing its structural and functional attributes, has been well documented [ 2- 4].
We approached this challenge by first identifying the most relevant functional attributes that has been well documented in cancer and then extracting this information to build a Boolean logic.
Differences in the efficacy and safety of various drugs in different racial groups have been well documented and can be attributed to differing rates of comorbid conditions, concomitant medication use, and underlying genetic variations in the enzymes involved in drug metabolism [ 27].
Tumor cells have been well recognized to show a distinctive attribute for metastasis to specific organs; the 1889 Stephen Paget's original "seed and soil" hypothesis was reported that the organ-preference patterns of tumor metastasis were the product of interactions between metastatic tumor cells (the seed) and their organ microenvironment (the soil) [ 3].
