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Scans were acquired 2 h after bolus injection to optimally visualize extrastriatal SERT binding, a technique that has been validated before [23].
Specificity of the GFP-antibody has been validated before (Poser et al. 2008, Fig. S1).
Several anti-Jmjd6 antibodies are commercially available, however, only one antibody has been validated before in a wildtype/Jmjd6 knockout context [29].
This has been validated before (22,25).
Similarly, VEGFA was knocked down using TRCN0000003343, the effectiveness of which has been validated before (Segarra et al., 2012).
Although suicide recording has been validated before in the Value Added Medical Products (VAMP) health resource, the precursor to the CPRD, it was based on a cohort of patients prescribed antidepressants and was done over 15 years ago 20.
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All instruments have been validated before the study start, including linguistic validation where needed.
The dimension methodology includes the robustness of the scientific methodology, and the validation of algorithms (e.g. Did the algorithms have been validated before bringing into business?).
This means that in future, in-cell proximity might have been "validated" before a motif discovery project is undertaken.
The SNP array method had been validated before clinical application and small numbers of cells from hESC lines were used, which was described in the report [ 24]. qPCR was used to validate the results of NGS and SNP array.
New SDRs and resignalling SDRs resulting from each of these runs were assumed to have been validated before the next run, hence, their counts, frequencies and statistical scores created a new baseline for the subsequent SSD runs to compare the resignalling criteria against.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com