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An increased level of LDLR protein has been shown to dramatically decrease toxic amyloid deposition in the brain [ 39] and vice versa experiments with cell cultures models of AD in both human and mouse show that increased expression of APP and Abeta downregulate LDLR expression [ 40].
On the contrary, use of low-sulfur fuel in a modern heavy-duty diesel engine has been shown to dramatically decrease the emission of 9-nitroanthracene along with many other nitrated-PAHs, but modestly increase the emission of 9-nitrophenanthracene (Liu et al., 2010).
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TNF- α monoclonal antibodies have been shown to dramatically decrease signs and symptoms of IBD and subsequently are key potential therapeutic agents [ 25, 26].
As counterions exhibiting mere electrostatic attractions have been shown to dramatically decrease the viscosity of ILs, future derivatives can be produced which should exhibit increased ion mobility, in turn enhancing the applicability of electrochrome functionalised ILs.
BDNF has been shown to dramatically upregulate neuropeptide Y [22], a vasoconstrictive sympathetic co-transmitter [23].
However, continuous passaging of C. jejuni NCTC11168 has been shown to dramatically affect its colonisation potential.
Indeed, PTEN depletion has been shown to dramatically increase MN survival in vivo.
Tissue factor expression has been shown to dramatically change tumour behaviour.
Properly placed shields have been shown to dramatically reduce operator eye dose [ 39, 40].
These have been shown to dramatically improve reaction/recognition time, due to their fast-paced nature.
The routine immunization with the heptavalent pneumococcal conjugate vaccine has been shown to decrease the incidence of vaccine-type antibiotic-resistant pneumococci both in invasive diseases; nasopharyngeal colonization was also dramatically decreased in vaccinated individuals and their contacts [ 5].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com