Sentence examples for has been refractory from inspiring English sources
Radiofrequency denervation is commonly used for the treatment of chronic facet joint pain that has been refractory to more conservative treatments, although the evidence supporting this treatment has been controversial.
Patients with intra-articular disorder who has been refractory to nonsurgical treatment over 3 to 6 months with persistent pain and limited function would require a consideration for surgical interventions (Figure 4) Figure 4 Flow diagram and treatment algorithm for patients with dentofacial deformity and TMD symptoms.
To this end, the Translational Behavioral Science Research Consortium was created by the National Heart ,Lung, and Blood Institute to identify promising, but underutilized findings from basic behavioral science that might have potential application for translation to clinical populations where behavioral change has been refractory to standard intervention approaches.
The recent introduction of tumor necrosis factor (TNF) blockers in the treatment of spondyloarthritis has offered the most hope in not only relieving symptoms and signs of both peripheral arthritis and enthesitis but also spinal disease, which often has been refractory to other agents.
Because of its highly repetitive nature, centromeric DNA has been refractory to sequencing.
Consequently, the molecular-genetics of the rDNA has been refractory to simple approaches aimed at revealing cause effect relationships.
The symptoms had been refractory to non-operative management.
All patients had been refractory to conservative non-invasive management and were referred to DHC for further evaluation.
Refractory headache was classified in those who had been refractory to all previous forms of therapy including β-blocker and anti depressants.
This novel method of gene silencing has substantial promise for elucidation of gene function in bacterial species that have been refractory to experimental introduction of exogenous DNA.
The CCH case had been refractory to many other treatments including ONS, thus the partial improvement achieved was been rated as meaningful by the patient.
