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The median OS for advanced disease has been prolonged by chemotherapy and with the advent of newer targeted therapies; this is likely to increase further.
1824, 85 L.Ed.2d 1985(1985) (STEVENS, J., concurring) ("If it appears that unmeritorious litigation has been prolonged merely for the purposes of delay, with no legitimate prospect of success, an award of double costs and damages occasioned by the delay may be appropriate".).
Life may have been prolonged in this patient population with the use of mechanical ventilation.
The debate was prolonged with passionate views over two books".
They now concede that his life has probably been prolonged from being at home with his family and receiving better medical care.
In circumstances where Type 2 reactions occur there has often been prolonged treatment with high dose β-lactam antibiotics.
The FDA-approved anti-VEGF antibody bevacizumab (Bev) is one such validated antiangiogenic therapeutic agent that, when used in combination with chemotherapy, has been shown to prolong survival in patients with metastatic colorectal cancer (CRC) (Hurwitz et al, 2004).
Aggressive cytoreductive therapy, including surgery (extrapleural pneumonectomy) in combination with chemotherapy and radiation (trimodality therapy), has been shown to prolong survival in selected patients with early MPM (Sugarbaker et al, 1996).
Intriguingly, exposure to LMWHs has been suggested to prolong survival in patients with malignant disease.
Trastuzumab is the first monoclonal antibody that has been shown to prolong life in patients with a malignant epithelial condition.
The addition of bevacizumab has been shown to prolong OS in patients with irinotecan-based regimens, but the data on patients treated with the combination chemotherapy containing oxaliplatin are more ambiguous.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com