The phrase "has been largely performed" is grammatically correct and can be used in written English.
You can use it when referring to a task or project that was done or completed to a large or significant degree. For example, "The project to restore the historic building has been largely performed and will be completed soon."
Although there are many diagnostic methods to detect C. difficile directly from stool samples, the nucleic acid-based approach has been largely performed in several laboratories due to its high sensitivity and specificity as well as rapid turnaround time.
Analysis of the microbiome has been largely performed at higher taxonomic levels (for example, genus, species) and focused primarily upon the 16S rRNA gene [ 44] but these analyses are now increasingly using full metagenomic data sets [ 45].
Stem cell lineage analysis in fish has been largely performed by transplantation or by DNA injection, but both methods require the analysis of hundreds of clones to exclude putative technical artifacts (Centanin et al., 2011; Tu and Johnson, 2011; Wong and Rapaport, 2009).
However biochemical analyses of dog heart PDE have been largely performed on mixed enzyme populations, sequence information is lacking and no PDE from dog heart has been cloned.
Developmental and morphological studies have been largely performed on human choroid plexus samples of either embryonic or post-mortem origin.
Pharmacokinetic studies of bumetanide have been largely performed in the context of treatment for fluid overload in cardiopulmonary disease in adults and critically ill term and preterm neonates.
To date, studies on hyperosmotic adaptation and salt tolerance in fungal species have been largely performed with the salt-sensitive model organism S. cerevisiae, for reasons of experimental convenience.
As it has been largely published, tests performed as a function of time have as a common characteristic high standard deviation values.
Outside diabetic ketoacidosis, ketone measurement is not routinely performed and has been largely used as a research tool to quantify cellular redox status.
See the video here The glam-rock singer shot to fame in the late 60s with Space Oddity but has been largely silent in recent years, not performing live since 2006 and rarely appearing in public since then.
The role of probiotics in gastrointestinal and allergic diseases has been largely assessed, but the number of studies performed so far in the field of respiratory tract infections is small, though some data show that probiotic administration might display clinical advantages.
