OR, odds ratio; CI, confidence interval For this variable, all occupations for each period were considered; a period was classified as "exposed" if the index indicated that the father had been "highly exposed" in at least one of his occupations during that period (Table 3).
Some fathers may have also worked in one of these plants, and could have been highly exposed to PCBs.
However, in order to be compensated, an individual case must have been highly exposed whereas AFs include also the (population) effects of lower levels of exposure.
On the other hand, associations could be overestimated since people with cancer who knew they had been highly exposed may have had a greater incentive to enroll in the study.
Hence, although d-glucaric acid concentrations are elevated in urine samples of individuals who have been highly exposed to dioxins, it does not appear to be sensitive enough in situations involving low-level environmental PCB exposure.
Recently, insulin resistance and toxicant-associated steatohepatitis (TASH), a form of NASH, were reported in nonobese chemical workers who had been highly exposed to vinyl chloride (Cave et al. 2010).
This likely led to underestimation of the number of exposed RNs but would have been highly specific.
Within this group 5 individuals had latent TB infection, 17 were highly exposed, and 9 were considered unexposed.
